May 24, 2009

nanosilver toxicity...do we get it yet?

Food storage material silver nanoparticles interfere with DNA replication fidelity and bind with DNA
Wenjuan Yang et al 2009 Nanotechnology

"The results showed that the replication fidelity of the rpsL gene was differentially compromised by all three kinds of nanosilver particle compared with that without nanosilver. This assay could be expanded and applied to any other materials to preliminarily assess their potential long-term toxicity as a food additive or biomedical reagent. Moreover, we found that nanosilver materials bind with genomic DNA under atomic force microscopy, and this might be an explanation for the compromised DNA replication fidelity".

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